CRC Press - Neurobiology Of TRP Channels (2017 EN)

Author: Tamara Luti Rosenbaum Emir (Editor)
Full Title: Neurobiology Of TRP Channels
Publisher: CRC Press; 1 edition (September 1, 2017)
Year: 2017
ISBN-13: 9781498755245 (978-1-4987-5524-5), 9781315152837 (978-1-315-15283-7)
ISBN-10: 1498755240, 1315152835
Pages: 327
Language: English
Genre: Biomedical Science: Neuroscience
File type: PDF (True, but nonnative Cover)
Quality: 9/10
Price: £114.00


During the last two decades, there has been an explosion of research pertaining to the molecular mechanisms that allow for organisms to detect different stimuli that is an essential feature for their survival. Among these mechanisms, living beings need to be able to respond to different temperatures as well as chemical and physical stimuli.

Thermally activated ion channels were proposed to be present in sensory neurons in the 1980s, but it was not until 1997 that a heat- and capsaicin- activated ion channel, TRPV1, was cloned and its function described in detail. This groundbreaking discovery led to the identification and characterization of several more proteins of the family of Transient Receptor Potential (TRP) ion channels.

Intensive research has provided us with the atomic structures of some of these proteins, as well as understanding of their physiological roles, both in normal and pathological conditions. With chapters contributed by renowned experts in the field, Neurobiology of TRP Channels contains a state- of- the- art overview of our knowledge of TRP channels, ranging from structure to their functions in organismal physiology.


Features:
— Reviews roles of TRP channels in several physiological processes of organisms
— Examines diseases related to malfunction of TRP channels
— Analyzes the most current knowledge on the complexity of the interactions of TRP channels with other proteins in different physiological systems
— Presents signaling pathways associated to the physiological functions of TRP channels
— Describes tissue-specific roles for various TRP channels

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