Author: Iuliana M. Lazar (Editor), Maria Kontoyianni (Editor), Alexandru C. Lazar (Editor) Full Title: Proteomics For Drug Discovery: Methods And Protocols Publisher: Humana Press; 1st ed. 2017 edition (August 15, 2017) Year: 2017 ISBN-13: 9781493972012 (978-1-4939-7201-2), 9781493972005 (978-1-4939-7200-5) ISBN-10: 1493972014, 1493972006 Pages: 302 Language: English Genre: Biomedical Sciences: Pharmacology File type: PDF (True) Quality: 10/10 Price: 117.69 € This book reflects the drug development community’s interest in proteomics methods by providing researchers with the necessary knowledge for the implementation of a number of basic experimental and bioinformatics protocols in the drug discovery research laboratory. The focus of the collection is on select protocols and methodologies that address the analysis of post-translational modifications, targeted protein quantification, protein-protein, protein-lipid, or protein-ATP interactions, in silico lead identification, protein arrays, tissue and cell extract preparation, labeling, chemoproteomics, and drug efficacy assessment. Emphasis was placed not just on methods that describe large-scale protein analysis, but also on ones that are amenable to future implementation in a high-throughput format. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Proteomics for Drug Discovery: Methods and Protocols aims to provide a deep knowledge of the fundamentals of disease biology as well the means that were developed for probing the complex biological milieu. ------------- Our members see more. Join us!