SPRI | Circadian Rhythms And Their Impact On Aging (2017 EN)

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  1. Kanka

    Kanka Well-Known Member Loyal User

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    Author: S. Michal Jazwinski (Editor), Victoria P Belancio (Editor), Steven M Hill (Editor)
    Full Title: Circadian Rhythms And Their Impact On Aging
    Publisher: pringer; 1st ed. 2017 edition (November 22, 2017)
    Year: 2017
    ISBN-13: 9783319645438 (978-3-319-64543-8), 9783319645421 (978-3-319-64542-1)
    ISBN-10: 3319645439, 3319645420
    Pages: 361
    Language: English
    Genre: Biomedical Sciences
    File type: EPUB (True), PDF (True)
    Quality: 10/10
    Price: 213.99 €


    Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book will examine the machinery that constitutes circadian systems and how they impact physiologic processes. It will also discuss how disturbances of circadian rhythms can lead to complex diseases associated with aging. Much of this treatment will focus on metabolism and genome stability. Importantly, the chapters in this book will encompass work in several different models, in addition to human. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.

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