Author: Guido Bocci (Editor), Giulio Francia (Editor) Full Title: Metronomic Chemotherapy: Pharmacology And Clinical Applications Publisher: Springer; 2014 edition (September 5, 2014) Year: 2014 ISBN-13: 9783662436042 (978-3-662-43604-2), 9783662436035 (978-3-662-43603-5), 9783662513194 (978-3-662-51319-4) ISBN-10: 3662436043, 3662436035, 3662513196 Pages: 295 Language: English Genre: Biomedical Sciences: Pharmacology & Toxicology File type: PDF (True) Quality: 10/10 Price: 155.99 € This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic. ------------- Our members see more. Join us!