Author: Alexandre Alexakis (Editor), Norbert Krause (Editor), Simon Woodward (Editor) Full Title: Copper-Catalyzed Asymmetric Synthesis Publisher: Wiley-VCH; 1 edition (March 31, 2014) Year: 2014 ISBN-13: 9783527332045 (978-3-527-33204-5) ISBN-10: 3527332049 Pages: 472 Language: English Genre: Chemistry: Organic Chemistry File type: EPUB (True), PDF (True, but nonnative Cover) Quality: 9/10 Price: 150.00 € This book reflects the increasing interest among the chemical synthetic community in the area of asymmetric copper-catalyzed reactions, and introduces readers to the latest, most significant developments in the field. The contents are organized according to reaction type and cover mechanistic and spectroscopic aspects as well as applications in the synthesis of natural products. A whole chapter is devoted to understanding how primary organometallics interact with copper to provide selective catalysts for allylic substitution and conjugate addition, both of which are treated in separate chapters. Another is devoted to the variety of substrates and experimental protocols, while an entire chapter covers the use on non-carbon nucleophiles. Other chapters deal with less-known reactions, such as carbometallation or the additions to imines and related systems, while the more established reactions cyclopropanation and aziridination as well as the use of copper (II) Lewis acids are warranted their own special chapters. Two further chapters concern the processes involved, as determined by mechanistic studies. Finally, a whole chapter is devoted to the synthetic applications. This is essential reading for researchers at academic institutions and professionals at pharmaceutical or agrochemical companies. ------------- Our members see more. Join us!
