Wiley - Oral Bioavailability Assessment: Basics And Strategies For Drug Discovery And... (2017 EN)

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  1. Kanka

    Kanka Well-Known Member Loyal User

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    Author: Ayman F. El-Kattan, Mike S. Lee (Series Editor)
    Full Title: Oral Bioavailability Assessment: Basics And Strategies For Drug Discovery And Development
    Publisher: Wiley; 1 edition (June 6, 2017)
    Year: 2017
    ISBN-13: 9781118916698 (978-1-118-91669-8), 9781118916933 (978-1-118-91693-3)
    ISBN-10: 1118916697, 111891693X
    Pages: 448
    Language: English
    Genre: Medicinal Chemistry > Drug Discovery & Development
    File type: PDF (True, but nonnative Cover)
    Quality: 9/10
    Price: 168.00 €

    Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development.
    • Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability
    • Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development
    • Explains how preclinical animal models – used in preclinical testing – and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development
    • Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS)
    • Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development
    Last edited by a moderator: Jul 23, 2018

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