Author: Per Hellman (Editor) Full Title: Primary Aldosteronism: Molecular Genetics, Endocrinology, And Translational Medicine Publisher: Springer; 2014 edition (March 29, 2014) Year: 2014 ISBN-13: 9781493905096 (978-1-4939-0509-6), 9781493905089 (978-1-4939-0508-9), 9781493946228 (978-1-4939-4622-8) ISBN-10: 1493905090, 1493905082, 1493946226 Pages: 233 Language: English Genre: Biomedical Sciences: Human Genetics File type: PDF (True) Quality: 10/10 Price: 179.98 € Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene – KCNJ5 – in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more. ------------- Our members see more. Join us!
